Jan 10, 2025
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Invited Applicants Only
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Grant Recipients
Lamiae Abdeladim, PhD University of California-Berkeley Pan-cortical Optical Brain Machine Interfaces for Complex Visual Percept Recreation
Lindsey Brown, PhD Princeton University Dynamical Systems and Control Approaches to Understanding and Shifting Individual Learning Trajectories in the Emergence of Neuropsychiatric Disease
Gregg Castellucci, PhD New York University Understanding Human Communication Using Neural, Behavioral, and Comparative Approaches
Kate Cavanaugh, PhD University of California—San Francisco Working Against the Clock: Leveraging Biophysics to Extend Female Reproductive Lifespan
Colwyn Headley, PhD Stanford University Bioengineering Mitochondria for Targeted Delivery
Natsumi Komatsu, PhD University of California-Berkeley Mapping Neurochemistry of the Brain with Near-Infrared Nanosensors and Deep-Brain Microscopy
Deepak Krishnamurthy, PhD University of California-Berkeley Microscale Biophysics of the Ocean
Iain Martyn, PhD University of California-San Francisco Mapping Human and Mouse Morphogenetic Decisions During Development with CARTOGRAPHER
Harold McNamara, PhD Princeton University Guiding Stem Cell Self-Organization with Optogenetic Circuits
Aran Nayebi, PhD Massachusetts Institute of Technology Building Integrative, Embodied Agents to Understand Natural Cognition
Luca Rosalia, PhD Stanford University Bio-Fabrication and Mechanobiology: A Biomimetic Approach to Modeling and Understanding Cardiovascular Diseases
Shunzhi Wang, PhD University of Washington Computational Design of Enveloped Protein Capsids for Delivery
Ismail Ahmed. PhD New York University Chemical Tools for Spatiotemporal Control and Detection of Neuropeptides in Behaving Animals
Linlin Fan. PhD Stanford University Probing synaptic and circuit plasticity mechanisms underlying learning and memory with all-optical electrophysiology
Avi Flamholz. PhD California Institute of Technology Predicting microbial CO2 production in global soils
Luis Hernandez-Nunez, PhD Harvard University The interoceptive balancing act: The neural computations underlying organ control
Richard Felix Horns, PhD California Institute of Technology RNA export for measurement and control of living cells
Carmel Howe, PhD Oregon Health & Science University Development of a low-cost 3D imaging system for rapid monitoring and targeted photorelease of ligands to identify driver neurons in the brain
Rebecca Pinals. PhD Massachusetts Institute of Technology A Multicellular Human Brain-on-Chip with Integrated Nanosensors to Visualize Neurodegenerative Disease Dynamics
Manuel Schottdorf, PhD Princeton University Deciphering cognition with geometry
Jessica Stark, PhD Stanford University Engineering Glycoimmunology
William Edward Allen, Ph.D Harvard University Reverse-Engineering Brain Aging and Rejuvenation
Sima Asadi, Ph.D. Massachusetts Institute of Technology Pathogen-Laden Respiratory Droplet Formation via Mucosalivary Fluid Fragmentation
Diego Calderon, Ph.D. University of Washington Application of multiplex reporter assays towards understanding trans-acting gene regulation
Gregory Handy, Ph.D. University of Chicago Developing theoretical neuroscience frameworks to include plasticity from diverse brain cell types
Freeman Lan, Ph.D. University of Wisconsin-Madison Understanding complex microbial systems using ultrahigh-throughput experimentation, computational modelling, and machine-learning
Maijia Liao, Ph.D. Yale University Biophysics and Molecular determinants of morphological scaling laws in developing dendrites
Leenoy Meshulam, Ph.D. University of Washington Bridging scales: from microscopic neural circuitry to macroscopic function
Samantha Petti, Ph.D. Harvard University Uncovering remote evolutionary links with next-generation homology search
Boyang Qin, Ph.D. Princeton University Tracing gene expression of single cells across lineages during bacterial biofilm formation and dispersal
Liat Shenhav, Ph.D. Rockefeller University Early prediction of pregnancy disorders using the vasculature of the eye
Andrew Yang, Ph.D. University of California-San Francisco Molecular tools to decipher communication across the blood-brain barrier
Kevin Dalton, PhD Harvard University Machine Learning Models for Next Generation X-Ray Diffraction Experiments
Rebecca Donegan, PhD Georgia Institute of Technology Heme as a nutrient source at the host-pathogen interface
Anne Draelos, PhD Duke University Adaptive Algorithms for Online Neural Modeling
Rogelio Hernandez-Lopez, PhD University of California-San Francisco A multiscale quantitative approach for engineering cellular therapies and disease modeling
Antentor Hinton, PhD University of Iowa Carver College of Medicine Reimaging, Restoring, and Repurposing Mitochondria and MERC networks
Christina Hueschen, PhD Stanford University Physical Biology of Parasites
Vira Kravets, PhD University of Colorado-Denver Beta cell networks and neural interactions in healthy and diabetic conditions
Ruth Marisol Herrera Perez, PhD Columbia University Engineering models to control cell communication in self-organizing systems
Rebecca Sherbo, PhD Harvard University Sustainable food out of thin air
Charlotte Strandkvist, PhD Harvard Medical School Studying cell fate decisions and dynamics with time-resolved single cell genomics
Longzhi Tan, PhD Stanford University Probing the 3D Chromatin and Spatial Transcriptomic Basis of Neurodevelopment, Social Behaviors, and Autism with Single-cell Precision
Ahmed S. Abdelfattah, PhD Brown University Probing and manipulating the neural circuitry of opiate addiction using novel optogenetic tools
Zibo Chen, PhD California Institute of Technology Molecular programming using de novo designed proteins
Yogesh Goyal, PhD University of Pennsylvania Biochemical trajectories guiding rare cell plasticity and therapy resistance in single cancer cells
Elizabeth R. Jerison, PhD Stanford University Migration and population dynamics in the zebrafish adaptive immune system
Stephanie E. Lindsey, PhD Stanford University Quantitation of early great vessel growth and remodeling
Brittany S. Morgan, PhD TBD* Cracking the molecular recognition code: capturing dynamic substructures with small molecules
Cristina Rodriguez, PhD University of California - Berkeley Decoding spinal cord neural circuits through advanced optical imaging methods
Julea Vlassakis, PhD University of California-Berkeley Precision oncology via single-cell proteomics
*award will be granted to faculty institution of award recipient
Steven Mark Banik, PhD Stanford University Reprogramming proteins for targeted degradation and intracellular trafficking
Jennifer Ann Noelani Brophy, PhD Stanford University Engineering organ development using synthetic genetic regulation
Fei Chen, PhD Massachusetts Institute of Technology Genomic tools for understanding spatial and dynamic organization of biological tissues
Víctor García-López, PhD Rice University Molecular machines target, disrupt cell membranes, and kill cancer cells and resistant bacteria
Livnat Jerby, PhD Massachusetts Institute of Technology Deciphering immune evasion mechanisms in cancer with single-cell technologies
Christina K. Kim, PhD Stanford University Simultaneous molecular activity recording and transcriptomics of brainwide neural ensembles
Joseph William Larkin, PhD University of California-San Diego Patterning microbial populations through collective dynamics
Jeffrey E. Markowitz, PhD Harvard Medical School Resolving the neural mechanisms of reinforcement learning through new behavioral and optical technologies
Sergey D. Stavisky, PhD Stanford University Brain-computer interfaces to actualize the movements and speech of people with paralysis
Jeffrey Robert Tithof, PhD University of Rochester Experimentally-validated simulations of cerebrospinal fluid flow through the brain’s perivascular network
Mark Wagner, PhD Stanford University Computations, recurrent dynamics, and learning in the cortex-cerebellum circuit underlying skilled behavior
Gozde Durmus, DPhil, PhD Stanford University Levitating rare biological materials to decode the fundamentals
Kirsten L. Frieda, PhD California Institute of Technology Recording cell histories in situ using MEMOIR
Walter Gabriel Gonzalez, PhD California Institute of Technology Dynamic control of brain activity and behavioral robustness
Brandon Helfield, PhD University of Toronto Biophysics and cell biology of ultrasound-assisted membrane permeabilization for targeted gene delivery
Daniel R. Hochbaum, PhD Harvard Medical School Parsing learning-dependent circuit remodeling from spatiotemporally resolved cell states
Chiamaka Denise Okafor, PhD Emory University Targeting steroid receptors by uncovering evolutionary mechanisms of activation
Nicolas Christian Pegard, PhD University of California-Berkeley Computational optical interfaces for neurosciences and systems biology
Calin Plesa, PhD University of California-Los Angeles Ubiquitous biosensing through engineered histidine kinases
Silvia Rouskin, PhD Massachusetts Institute of Technology Understanding RNA structure heterogeneity and its role in gene expression and disease
Geoffrey Schiebinger, PhD Massachusetts Institute of Technology Analyzing developmental processes with optimal transport
Shahrzad Yazdi, PhD Massachusetts Institute of Technology Bridging the origin and function of flows in developmental biology
Scott E. Boyken, PhD University of Washington Programmable protein interaction specificity to engineer and interrogate cellular signaling
Gregg A. Duncan, PhD Johns Hopkins University Microscale airway surface liquid interactions and their role in obstructive lung diseases
Felipe Garcia Quiroz, PhD Rockefeller University Repetitive elements of life: from genomes to proteins and material systems
Kelley Harris, PhD Stanford University Decoding the evolutionary history of DNA replication fidelity from whole genome sequences
Felix JH Hol, PhD Stanford University Eco-evolutionary dynamics of mosquito-borne viruses
Ashok Litwin-Kumar, PhD Columbia University Modeling distributed olfactory learning in rodents and insects
Po-Ru Loh, PhD Harvard School of Public Health Toward an early-warning system for leukemia: Characterizing mosaic copy number abnormalities
Tatiana V. Mishanina, PhD University of Wisconsin-Madison Visual-kinetic studies of pausing by bacterial RNA polymerase using time-resolved cryo-EM
Octavio Mondragon-Palomino, PhD California Institute of Technology In situ dissection of bacteria-bacteria interactions on the mucosa of the mammalian gut
Priya Moorjani, PhD Columbia University Learning about the rate and chronology of human evolution
Amy Elizabeth Shyer, PhD University of California-Berkeley Investigating mechano-chemical mechanisms of mesenchymal morphogenesis in skin and bone
Amy M. Weeks, PhD University of California-San Francisco Untangling the protease web: Chemical and enzymatic probes for dissection of proteolytic signaling in immune cells
Ahmet F. Coskun, Ph.D. California Institute of Technology Computational single molecule imaging and barcoding: Exploring cellular identity at the single cell transcript level
Alexander G. Huth, Ph.D. University of California-Berkeley Comprehensive functional mapping of human cortex using generative models
Ashley Laughney Bakhoum, Ph.D. Sloan-Kettering Institute Uncovering transcriptional vulnerabilities in latent metastasis
Michael J. Mitchell, Ph.D. Massachusetts Institute of Technology High-throughput in vivo nucleic acid delivery screening via molecular barcoding of nanoparticles for bone marrow-related diseases
Arthur Prindle, Ph.D. University of California-San Diego Electrical signaling and multicellular organization
Adrianne Marie Rosales, Ph.D. University of Colorado-Boulder Dynamic viscoelastic hydrogels to study mechanisms of fibrosis
David M. Schneider, Ph.D. Duke University Neural circuits for making predictions and learning from mistakes
Amy Wesolowski, Ph.D. Princeton University Impact of human travel on infectious disease dynamics
Jing Yan, Ph.D. Princeton University Resolving and analyzing living bacterial biofilms at the single cell level
Weijian Yang, Ph.D. Columbia University Holographic mapping and manipulation of neuronal microcircuits
Ariana E Anderson, Ph.D. University of California-Los Angeles It's all in your head: isolating the placebo effect in the brain to reduce drug development costs
Amit Choudhary, Ph.D. Harvard University / Broad Institute Snakes, antioxidants, and diabetes
Matthew C Good, Ph.D. University of California-Berkeley Cell size and shape dependence of intracellular assembly and signaling
Prashant Mali, Ph.D. Harvard Medical School Engineering normal and diseased liver organogenesis
Nikhil S Malvankar, Ph.D. University of Massachusetts-Amherst Direct visualization of charge flow in individual native biomolecules
Elizabeth A Nance, Ph.D. Johns Hopkins University Nanoparticle-mediated targeted therapies for pediatric brain disorders
Elizabeth Hesper Rego, Ph.D. Harvard School of Public Health Drug use on the single cell level: differential antibiotic susceptibility of mycobacterial cells using fluorescent reporters.
Ramkumar Sabesan, Ph.D. University of California-Berkeley School of Optometry Studying visual function on a cellular scale
Kimberly Murley Stroka, Ph.D. Johns Hopkins University School of Medicine Engineering blood-brain barrier mechanobiology in tumor metastasis
Michael D. Vahey, Ph.D. University of California-Berkeley School of Public Health Uncovering the dynamics of enveloped virus assembly
Heng Xu, Ph.D. Baylor College of Medicine Deciphering stochastic transcriptional regulation at the single-event level
Xin Zhang, Ph.D. Scripps Research Institute Scrutinizing the cellular and molecular mechanisms that create and maintain the functional proteome using chemical probes
Gregory R. Bowman, Ph.D. University of California - Berkeley Decrypting cryptic allosteric sites resulting from protein flexibility
Yaniv Erlich, Ph.D. Whitehead Institute for Biomedical Research Dissecting complex phenotypes using web 2.0 social networks
Stephanie I. Fraley, Ph.D. Johns Hopkins University School of Medicine Digitizing microRNA: integrated profiling and discovery for rapid, quantitative, and broad-scale detection in infectious disease
Hernan G. Garcia, Ph.D. Princeton University Wiring up the synthetic fly
Karen E. Kasza, Ph.D. Memorial Sloan-Kettering Cancer Center Mechanical cues coordinating cell behaviors during morphogenesis
Gabriel Kwong, Ph.D. Massachusetts Institute of Technology Nanoparticles that amplify biomarkers in vivo for ultrasensitive metastasis monitoring
Megan N. McClean, Ph.D. Princeton University Optogenetic and microfluidic tools for generating dynamic inputs to interrogate and control biological networks
Mikhail G. Shapiro, Ph.D. University of California - Berkeley Genetically encoded reporters for sensitive non-invasive imaging of biological function
Paul A. Sigala, Ph.D. Washington University Mechanistic probes of heme metabolism in malaria parasites
Bo Wang, Ph.D. University of Illinois-Urbana-Champaign In vivo imaging and functional genomic analysis of stem cells in human parasitic worm schistosoma
Buz M. Barstow, Ph.D. Harvard Medical School Evolving the limits of metabolism and in vivo catalysis
ShiNung Ching, Ph.D. Harvard Medical School Towards treatments in disorders of consciousness and new models of general anesthesia
Kwanghun Chung, Ph.D. Stanford University Clear, Lipid-exchanged, Anatomically Rigid, Imaging/immunostaining-compatible, Tissue hYdrogel (CLARITY) technology for high-throughput and high-content whole tissue analysis
Robert Gregg, Ph.D. Northwestern University From machine to biomimetic control in robot-assisted walking
Maureen E. Hillenmeyer, Ph.D. Stanford University In vivo synthetic evolution of bioactive natural products
Allon Moshe Klein, Ph.D. Harvard Medical School Defining patterns and mechanisms of stem cell fate choice
Sergey A. Kryazhimskiy, Ph.D. Harvard University Predicting evolution in microbial populations
Heather J. Kulik, Ph.D. Stanford University Deciphering the role of the protein scaffold in enzyme catalysis with fast and accurate computation
Lulu Qian, Ph.D. California Institute of Technology Exploring and re-realizing the principles of information processing in biology using artificial nucleic-acid systems
Jesse G. Zalatan, Ph.D. University of California - San Francisco Entropic contributions to efficiency in biochemical networks
Award Timeline
Sep 04, 2024
Letter of Intent Deadline
Nov 25, 2024
Invites for full proposal
Jan 10, 2025
Application Deadline
Apr 22 - 23, 2025
Interviews
Jun 01, 2025
Notice of Award
Jul 01, 2025
Award Start Date
Jun 30, 2030
Award End Date